To compare the effects of buprenorphine with levobupivacaine and buprenorphine with ropivacaine in epidural anaesthesia

To study the efficacy of buprenorphine with levobupivacaine and buprenorphine with ropivacaine in epidural anaesthesia - One year randomized clinical trail

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/05/033880

Enrollment

Registered

2021-05-31

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: buprenorphine with levobupivacaine: 0.5% levobupivacaine 15ml (intermittent dose 5ml every 5min) + Inj Buprenorphine 150mcg in epidural anaesthesia Control Intervention1: buprenorphine

Eligibility

Inclusion criteria

Inclusion criteria: Informed written Consent American Society of Anaesthesiologists physical status I and II. Age between 20-45 years. Patients Undergoing lower abdominal surgery under epidural anaesthesia

Exclusion criteria

Exclusion criteria: Hypersensitivity to amide local anaesthetic drugs Neurological disorders, Cardiac disease, pre-existing bleeding disorder. Local infections at the site Patients who do not fulfill inclusion criteria

Design outcomes

Primary

Measure	Time frame
Comparison of onset of action of sensory and motor block and the duration of action of buprenorphine with levobupivacaine and buprenorphine with ropivacaineTimepoint: 0min,5min,10min,15min,20min, 25min,30min,45min,60min,75min,90min,105min,120min	—

Secondary

Measure	Time frame
Comparison of hemodynamic effects like blood pressure, heart rate, spo2 in two groupsTimepoint: 0min,5min,10min,15min,20min, 25min,30min,45min,60min,75min,90min,105min,120min	—

Countries

India

Contacts

Public ContactPRUTHVI D HIREMATH

JAWAHARLAL NEHRU MEDICAL COLLEGE

kedareshvara@gmail.com9886375154

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026