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Comparison of Bolus vs Continuous feeding in mechanically ventilated children

Continuous feeding versus bolus feeding via nasogastric tube in mechanically ventilated children - an open-label randomized controlled trial - NiVeC Trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/05/033865
Enrollment
64
Registered
2021-05-29
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Using Continuous feeding through nasogastric tube for Pediatric ventilated children: Start feeds at 25% of target feed, by continuous infusion of total energy, by infusion pump or gravi
use incremental feeding, advance to 50% on D2 and Final Target on D3,Target feeding is calculated by age appropriate by ICMR-National Institute of Nutrition,India Control Intervention1: BOLUS Gastric

Sponsors

Department Of Pediatrics
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All ventilated children aged from 1 month to 18 years admit in PICU who :- 1. have conserved gastrointestinal function 2. require >72 hours of ventilation 3. were initiated enteral nutrition within the first 48 hours of PICU admission 4. gave consent for participation in the study.

Exclusion criteria

Exclusion criteria: 1.Primary gastrointestinal pathology or surgery; 2. Those with percutaneous gastrostomy tubes, intestinal fistula, obstruction, necrosis, peritonitis . 3. EN not started within 48 hours, or EN started prior to PICU admission; 4. Death or discharge before 72 hours of observation; 5. Contraindication to enteral diet; 6. Intolerance to the prescribed nutrients or infusion regimen.

Design outcomes

Primary

MeasureTime frame
Time to reach target feed between continuous vs bolus feeding in pediatric ventilated patients. Timepoint: 72 Hours

Secondary

MeasureTime frame
To see following comparisons between continuous and bolus feeding 1. Episodes of intolerance (Vomiting, increased GRV). 2. Incidence of ventilator associated pneumonia. 3. Length of hospital stay. 4. Effect on blood biochemistry ( Na, K, Blood Sugar, PO4 ). 5. Proportion of children with EN failure. 6. Overall effect on mortality.Timepoint: 72 Hours

Countries

India

Contacts

Public ContactDr Soumen Roy Sourov

All India Institute Of Medical Sciences,Rishikesh

rishibolia@yahoo.co.in8279284509

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026