Role and mechanism of action of High Definition Transcranial Direct Current Stimulation in reducing Auditory Hallucinations in Schizophrenia Patients

Neuromodulatory effects of adjunctive High-definition Transcranial Direct Current Stimulation (HD-tDCS) on auditory verbal hallucinations in Schizophrenia patients: A sham controlled Diffusion Tensor Imaging study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/05/033858

Enrollment

Registered

2021-05-28

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F20- Schizophrenia

Interventions

Intervention1: High Definition Transcranial Direct Current Stimulation (HDtDCS): ACTIVE High Definition Transcranial Direct Current Stimulation (2 sessions a day for 5 days, Total 10 sessions) in the

Eligibility

Inclusion criteria

Inclusion criteria: Schizophrenia patients having prominent auditory verbal hallucinations, who are right handed and gave written informed consent.

Exclusion criteria

Exclusion criteria: Comorbid neurological or psychiatric disorder, comorbid substance dependence, metallic implants, received ECT in past 6 months.

Design outcomes

Primary

Measure	Time frame
Change in PSYRATS AH & PANSS scoreTimepoint: Assessed at the completion of adjunctive HD-tDCS & 4 week after completion	—

Secondary

Measure	Time frame
Change in the FA value in Left Arcuate FasciculusTimepoint: At the completion of adjunctive HDtDCS & 4 week after completion	—

Countries

India

Contacts

Public ContactDr Sanjay Kumar Munda

Central Institute of Psychiatry

drsanjaymunda@gmail.com8797641082

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026