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Comparing the combination of dexmedetomidine and paracetamol versus paracetamol alone following open abdominal surgeries in a medical college hospital in chengalpattu district

COMPARATIVE STUDY OF DEXMEDETOMIDINE PLUS PARACETAMOL VERSUS PARACETAMOL ALONE IN POSTOPERATIVE PAIN RELIEF FOLLOWING LAPAROTOMY SURGERY IN TERTIARY CARE HOSPITAL,CHENGALPATTU DISTRICT.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/05/033849
Enrollment
84
Registered
2021-05-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: Dexmedetomidine with paracetamol: Group A will receive Inj.Paracetamol 1g + Inj.Dexmedetomidine 1mcg/kg in 100ml IV Control Intervention2: Paracetamol alone: Group B will recei

Sponsors

N SIVASELVI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adult patient aged between 18-60 years. 2. Patients belonging to ASA class 1 and 2.

Exclusion criteria

Exclusion criteria: 1. Pregnancy and lactation. 2. Obese patient with BMI >30. 3. Patients having, a) Uncontrolled hypertension/ diabetes mellitus. b) Cardiac diseases, Hepatic diseases c)Allergic to local anesthetic and Dexmedetomidine. 4.Emergency cases.

Design outcomes

Primary

MeasureTime frame
To compare the duration of Post-operative analgesia, Time for first rescue analgesia, Total analgesic requirements among the two groups. Timepoint: Post operatively, the patients in both the groups were observed for 24 hours and recording were done at: 0 hr (as soon as the patient was shifted), 1hr, 3hr, 6hr, 9hr, 12hr, 18hr and 24hrs.

Secondary

MeasureTime frame
To assess the Hemodynamic status like (Heart rate, Systolic blood pressure, Diastolic blood pressure, Mean arterial pressure) and Side effects such as nausea, Vomiting.  Timepoint: Post operatively, the patients in both the groups were observed for 24 hours and recording were done at: 0 hr (as soon as the patient was shifted), 1hr, 3hr, 6hr, 9hr, 12hr, 18hr and 24hrs.

Countries

India

Contacts

Public ContactN SIVASELVI

Shri sathya sai medical college and research institute.

dr.vijay@live.in9444877188

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026