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To compare the haemodynamic stabilizing effect of Etomidate in a group of hypertensive patients and another group of normotensive patients undergoing abdominal surgeries under general anesthesia.

Comparison of Haemodynamic Stabilizing Effect of Etomidate in Hypertensive versus Normotensive patients undergoing Abdominal surgeries under General anesthesia, an Interventional prospective study at SMS Medical College and Hospital, Jaipur during study period 2020-2021

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/05/033801
Enrollment
112
Registered
2021-05-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I119- Hypertensive heart disease withoutheart failure Health Condition 2: I158- Other secondary hypertension

Interventions

Intervention1: Injection Etomidate 0.3mg/kg given intravenously.: Injection Etomidate 0.3mg/kg given intravenously as ( single bolus dose)inducing agent in hypertensive patients undergoing abdominal s

Sponsors

SMS MEDICAL COLLEGE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1 and 2 Patients undergoing abdominal surgeries under general anesthesia Normal patients and those with treated hypertension Weight 40-80kg

Exclusion criteria

Exclusion criteria: Patients with untreated or uncontrolled hypertension Patient not willing to give consent Patient with baseline blood pressure less than 100/60mmHg and more than 160/110mmHg limits. History of allergy or hypersensitivity to Etomidate. Patients with unstable coronary arterial diseases. Patients with diabetes mellitus,pheochromocytoma, adrenal cortex insufficiency. Patients who are more than 30% over their ideal body weight. Patients undergoing laparoscopic surgeries.

Design outcomes

Primary

MeasureTime frame
To compare the Haemodynamic stabilizing effect of etomidate in hypertensive versus normotensive patients undergoing abdominal surgeries with general anesthesia by determining the difference of change in haemodynamic parameters in both the groupsTimepoint: First 10minutes after intubation—

Secondary

MeasureTime frame
To determine the difference in percentage of cases who may experience side effects in both group.Timepoint: 24hours—

Countries

India

Contacts

Public ContactDr Deepak Shanker S

Department of anesthesiology, SMS Medical college

purohitalaka@gmail.com8003399995

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026