FindTrial
Sign In

To study the effect of steroid use during treatment of severe Covid 19 on steroid axis function during 6 month post covid period.

Study to evaluate Hypothalamo Pituitary Adrenal axis during 6 months post Covid period - HPA PC

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/05/033799
Enrollment
60
Registered
2021-05-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere

Interventions

None listed

Sponsors

Prof Dr Jayanthy Ramesh
Lead Sponsor
Sai Institute of Endocrinology
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: diagnosed moderate or severe Covid 19 by RTPCR or Rapid Antigen Test(RAT) or HRCT thorax, admitted, treated and discharged from CSR Block, King George Hospital. Those patients who were hospitalised and have received steroid treatment for less than 14days. Those who give consent to participate in the study

Exclusion criteria

Exclusion criteria: Pregnant individuals Patients receiving glucocorticoids for any indication prior to hospital admission K/c/o primary/secondary adrenal insufficiency/ cortisol excess states Patients with Chronic kidney disease, Chronic liver disease, Coronary artery disease , Cerebrovascular accident Smokers/ Chronic alcoholism

Design outcomes

Primary

MeasureTime frame
Hypothalamo pituitary axis suppression, demonstrated by ACTH stimulated cortisol less than 18 mcg/dlTimepoint: 3 months and 6 months—

Secondary

MeasureTime frame
to coreelate between disease severity and HPA axis suppressionTimepoint: 3 month and 6 month—

Countries

India

Contacts

Public ContactShyam Sundar C M

Andhra Medical College

drjayanthyramesh@gmail.com7674025445

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026