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Role of zinc, magnesium and budesonide gargling on sore throat after surgery

Comparative efficacy of preoperative zinc, magnesium and budesonide gargles on the incidence and severity of postoperative sore throat (POST) in patients undergoing general anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/05/033741
Enrollment
180
Registered
2021-05-24
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: T885- Other complications of anesthesia

Interventions

Intervention1: Preoperative zinc, magnesium and budesonide gargles for postoperative sore throat (POST): A 30 ml solution prepared in a 50 cc syringe will be used for gargling by the patients in each

Sponsors

Government Medical College and Hospital Sector Chandigarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. American Society of Anaesthesiologists (ASA) physical status Iââ?¬â??II 2. Patients undergoing elective surgery under GA 3. Endotracheal intubation as definitive airway 4. Duration of surgery ââ?°Â¤ 6 hours 5. Supine position

Exclusion criteria

Exclusion criteria: 1. Patients with a history of pre-operative sore throat, asthma, chronic obstructive pulmonary disease, gastro-esophageal reflux disease (GERD) 2. Oral or head and neck surgeries 3. Modified Mallampati Grade>II 4. Known allergies to study drugs 5. More than one attempt at intubation 6. Anticipated difficult airway 7. Traumatic intubation 8. Patients who are unable to sit or have cervical spine injury 9. Pregnancy 10. Morbid obesity (BMI >35 kg/m2)

Design outcomes

Primary

MeasureTime frame
Incidence of Postoperative Sore Throat (POST)Timepoint: At immediate recovery (0 h), 2, 4, 6, 8, 12 and 24 h post-operatively.

Secondary

MeasureTime frame
Severity of Postoperative Sore Throat (POST)Timepoint: At immediate recovery (0 h), 2, 4, 6, 8, 12 and 24 h post-operatively.;To study the adverse effects associated with administration of the study drugs.Timepoint: 24 hours

Countries

India

Contacts

Public ContactDr Richa Saroa

Government Medical College and Hospital, Sector 32B, Chandigarh

sanjeev_palta@yahoo.com9646121523

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 6, 2026