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Placental growth factor and haeme indices to predict gestational diabetes mellitus

Role of Maternal serum placental growth factor and hematological parameters at 11â??14 weeks of gestation to predict gestational diabetes mellitus: A Prospective observational study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/05/033724
Enrollment
320
Registered
2021-05-21
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O244- Gestational diabetes mellitus

Interventions

None listed

Sponsors

Dr Mounika Koduri
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Singleton pregnancies at 11-14 weeks of gestation, at the time of combined screening for aneuploidy and preeclampsia by ultrasound scan and maternal serum biochemistry, who come to obstetrics and gynaecology OPD of Kasturba Hospital Manipal for regular ANC checkup.

Exclusion criteria

Exclusion criteria: Exclusion Criteria: 1)Women who have been diagnosed with hypertensive disorders in pregnancy 2)Previous pregnancy complicated with Gestational diabetes mellitus (GDM) 3)Pre-existing diabetes mellitus detected by HbA1C >6 4)Pregnancies with chromosomal abnormal fetuses or structural defects at 11-14 weeks 5)Pregnancies diagnosed with severe Early onset IUGR 6)Those who are not willing to participate in the study.

Design outcomes

Primary

MeasureTime frame
1) Diagnosis of GDM and its correlation with PlGF and blood parameter values at 11-14 weeks 2) Correlation of Gestational age at delivery (in weeks), Birth weight of baby (in grams), Proportion of GDM with NICU admission 24 hours, rate of Live baby at the time of discharge to PIGF values.Timepoint: 1) Diagnosis of GDM and its correlation with PlGF and blood parameter values at 11 a 14 weeks 2) Correlation of Gestational age at delivery (in weeks), Birth weight of baby (in grams), Proportion of GDM with NICU admission 24 hours, rate of Live baby at the time of discharge to PIGF values.

Secondary

MeasureTime frame
2) Correlation of Gestational age at delivery (in weeks), Birth weight of baby (in grams) at 36-40 weeks Proportion of GDM with NICU admission 24 hours, rate of Live baby at the time of discharge to PIGF values.Timepoint: 2) Correlation of Gestational age at delivery (in weeks), Birth weight of baby (in grams),at 36-40 weeks Proportion of GDM with NICU admission 24 hours, rate of Live baby at the time of discharge to PIGF values.

Countries

India

Contacts

Public ContactMounika koduri

KASTURBA MEDICAL COLLEGE MANIPAL

bssujata@gmail.com8660778169

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026