Reminerlising potential and longevity of sealants with and without incorporation of silver nanoparticles

Comparative evaluation of microleakage, microhardness, antimicrobial efficacy and remineralizing potential of pit and fissure sealants with and without incorporation of silver nanoparticles

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/05/033663

Enrollment

Registered

2021-05-18

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K025- Dental caries on pit and fissure surface

Interventions

Intervention1: Silver Nanoparticles: Silver nanoparticles were mixed with conventional pit and fissure sealants and cures on permanent first molars Control Intervention1: Conservative pit and fissure

Eligibility

Inclusion criteria

Inclusion criteria: 1. Fully erupted permanent molar on each side of lower jaw indicated for pit and fissure sealants 2. Informed Consent from the caretaker

Exclusion criteria

Exclusion criteria: 1. Partially erupted teeth 2. Parafunctional Habits 3. Medically compromised children 4. Silver allergy patients 5. Deep caries

Design outcomes

Primary

Measure	Time frame
Addition of Silver nanoparticles to different pit and fissure sealants improve microhardness, microleakge and antibacterial properties of conventional sealantsTimepoint: Addition of Silver nanoparticles to different pit and fissure sealants improve microhardness, microleakge and antibacterial properties of conventional sealants at baseline, 3 months and 6 months	—

Secondary

Measure	Time frame
NOT APPLICABLETimepoint: NOT APPLICABLE	—

Countries

India

Contacts

Public ContactManvi Malik

I.T.S.-C.D.S.R. Dental College, Ghaziabad

dr.manvimalik@gmail.com919868128011

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026