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Is combination of buccal plus palatal injection better than the buccal alone during the endodontic treatment of maxillary molars using 2% lidocaine and 4articaine with same adrenaline concentration- A clinical study

Comparison in the anesthetic efficacy of buccal, buccal plus palatal infiltration of 2% lidocaine and 4% articaine buccal infiltration in vital symptomatic maxillary molars: a prospective double blind randomized clinical trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/05/033659
Enrollment
60
Registered
2021-05-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: LIDOCAINE 2%: To compare the efficacy of buccal, buccal plus palatal infiltration with 2% lidocaine and buccal infiltration with 4% articaine alone to achieve pulpal anaesthesia Control

Sponsors

Department of Oral Health Science Centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: The inclusion criteria for the study were as follows: moderate to severe pain in the maxillary first molar, a prolonged response to cold testing with an ice stick and an electric pulp tester (Kerr Pulp Tester; Analytic Technology Corp, Redmond, WA), the absence of any periapical radiolucency on radiographs except for a widened periodontal ligament, a vital coronal pulp on access opening, and the ability of the subject to understand the use of pain scales. The subjects were in good health, and none were taking any medication that would alter pain perception, as determined by oral questioning and a written questionnaire.

Exclusion criteria

Exclusion criteria: The exclusion criteria for the study were as follows: subjects younger than 18 years of age or older than 50 years of age, any known sensitivity to either 2% lidocaine or 4% articaine or epinephrine, patients having active pain in more than 1 maxillary molar, subject taking any pain-relieving medication including over-the-counter analgesics at least 12 hours before enrollment in the study, and swelling near the tooth in question and having a tooth not suitable for simple restorative treatment because of extensive caries or periodontal problems.

Design outcomes

Primary

MeasureTime frame
Buccal infiltration injection alone effective in the maxillary molars pulpal anesthesiaTimepoint: 2 hours

Secondary

MeasureTime frame
3. 4% articaine with adrenaline is more effective than 2% lidocaine with adrenaline as an infiltration anaestheticTimepoint: 2 hours

Countries

India

Contacts

Public ContactUmesh KUMAR

Pgimer

odharmani911@gmail.com09862969792

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026