Randomized control trial to compare cautery (heated loop) versus non heated (cold cup) method for restaging of bladder cancer

Randomized Control Trial on TUR Loop versus Cold cup biopsy for Restage in Carcinoma Urinary Bladder

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/05/033608

Enrollment

120

Registered

2021-05-13

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N33- Bladder disorders in diseases classified elsewhere Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Cold cup Biopy: Biopsy using cold cup biopsy forceps for restage biopsy in Carcinoma Urinary Bladder patients under Anaethesia Control Intervention1: TUR Loop Biopsy: Transurethral biop

Eligibility

Inclusion criteria

Inclusion criteria: All patients who need restage TURBT as per standard treatment guidelines (Ta high grade,T1)

Exclusion criteria

Exclusion criteria: 1. Not giving consent to participate in study. 2. Residual tumor after TURBT

Design outcomes

Primary

Measure	Time frame
1. To compare adequacy of biopsy obtained by cold cup versus cautery loop. 2. To compare the histomorphological features in the biopsy samples obtained by these two methods. Timepoint: 4 weeks	—

Secondary

Measure	Time frame
1. To compare cancer pick up rate on restage TURBT for those who undergo TURBT at our institute versus those done elsewhere 2. To compare the number of obturator jerks and bladder perforations, duration of catheterization and hospital stay between the two techniques. Timepoint: 1. 1 month 2. 1 week	—

Countries

India

Contacts

Public ContactAmlesh Seth

AIIMS New Delhi

amlesh.seth@gmail.com9868397433

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026