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A study to compare the beneficial effects between the drug ephedrine and intravenous fluid ringer lactate in the prevention of maternal hypotension during spinal Anesthesia

A comparative study between the effects of crystalloid preloading and prophylactic ephedrine infusion in the prevention of maternal hypotension during spinal Anesthesia for cesarean section

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/05/033574
Enrollment
152
Registered
2021-05-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O82- Encounter for cesarean delivery without indication

Interventions

None listed

Sponsors

Gaurav Shybinth Sathyavrdhan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Gravida with term gestation 2. Singleton pregnancy 3.ASA physical status 2 4.Uncomplicated pregnancy 5.Undergoing elective LSCS under spinal anesthesia 6.Normal fetal heart rate 7.Height > 150 cms to 8.Age group 18 -30 years

Exclusion criteria

Exclusion criteria: 1.Patient refusal to the study. 2.Multiple gestation 3.Preterm gestation 4.ASA physical status 3 & above 5.Drug allergy 6.Contraindications to neuraxial analgesia 7.Caesarean case with fetal distress 8.Emergency Caesarean section 9.Patients with gestational hypertension

Design outcomes

Primary

MeasureTime frame
Maternal Hemodynamic variables :Heart Rate (HR), Systolic Blood Pressure(SBP), Diastolic Blood Pressure (DBP) and Mean Arterial Pressure (MAP) -Total dose of Ephedrine administered post-prophylactic dosing -Total volume of I.V.Fluids used Timepoint: June 2022

Secondary

MeasureTime frame
-Demographic variable:Age, Height,Weight,BMI -Other side effects: Nausea, Vomiting, Shivering and Allergic reactions Timepoint: July 2021 and January 2022

Countries

India

Contacts

Public ContactGaurav Shybinth Sathyavrdhan

Kasturba medical college Mangaluru

Shaila.kamath@manipal.edu9844090231

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026