FindTrial
Sign In

Effect of radiofrequency burning of compressed nerve root in low back pain patients and study its effect on CSF markers (IL6, IL8)

Effect of Dorsal Root Ganglion Pulsed Radiofrequency treatment in chronic lumbar radicular pain: a prospective interventional study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/05/033556
Enrollment
38
Registered
2021-05-11
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M00-M99- Diseases of the musculoskeletal system and connective tissue

Interventions

Intervention1: Pulsed radiofrequency ablation: Radiofrequency lesioning of dorsal root ganglion of spinal cord in low back pain patients and study CSF inflammatory markers before and after the procedu

Sponsors

All india institute of medical sciences Rishikesh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.lumbosacral radicular pain with dermatomal pattern of pain distribution 2. Duration of pain > 3 months 3. MRI confirms level and extent of nerve root impingement with disc herniation

Exclusion criteria

Exclusion criteria: patient refusal history of previous spine surgery or soine injury local site infection pregnancy, breast feeding severe systemic diseases other inflammatory neurological conditions, autoimmune diseases cauda equina syndrome coagulopathy, on anticoagulants malignancy any spinal deformity or fracture or raised intracranial pressure psychiatric or cognitive illness alcohol or drug abuse red flag sign

Design outcomes

Primary

MeasureTime frame
To assess pain relief following Pulsed Radiofrequency of the Dorsal root ganglion by Numerical Rating Scale (NRS) and compare pre-procedure scores with that of post-procedure scores Timepoint: at baseline (pre-procedure), 2 weeks, 3 months—

Secondary

MeasureTime frame
1. To evaluate Serum IL6 level in lumbar radicular pain patients and compare pre-RFA levels with that of 3 months post-RFA. 2. To identify correlation between intensity of pain and Serum IL-6 level 3. To assess the functional status by Modified Oswestry Disability Questionnaire (MODQ at baseline, 2 weeks, 3 months) and compare pre-procedure score with that of post-procedure score. 4. To assess any adverse effects and the complications due to the procedure Timepoint: pre-procedure and 3 months post-procedure—

Countries

India

Contacts

Public ContactSonal Goyal

All india institue of medical sciences Rishikesh

ajitdr.ajit@gmail.com9910789377

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026