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Hypothyroidism following radiotherapy in patients with head and neck cancer.

Hypothyroidism following definite radiotherapy in patients with head and neck cancer; prospective observational study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/05/033534
Enrollment
100
Registered
2021-05-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C01- Malignant neoplasm of base of tongue Health Condition 2: C139- Malignant neoplasm of hypopharynx,unspecified Health Condition 3: C12- Malignant neoplasm of pyriform sinus Health Condition 4: C090- Malignant neoplasm of tonsillar fossa Health Condition 5: C052- Malignant neoplasm of uvula Health Condition 6: C100- Malignant neoplasm of vallecula

Interventions

Intervention1: nil: nil Control Intervention1: T3, T4, TSH, Anti Tg, Anti TPO and volume of thyroid received and dose of radiotherapy.: TPO antibody,Anti Tg antibody and T3, T4, TSH estimation Radiati

Sponsors

Indira Gandhi Medical College Shimla
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a. all consecutive patients of head and neck confirmed on histopathology visiting regional cancer centre of IGMC planned to undergo definitive radiotherapy and who are free of hypothyroidism at base line consenting to participate following informed consent would be enrolled in the study. The subsites included will be oral cavity, oropharynx, hypo-pharynx and larynx .

Exclusion criteria

Exclusion criteria: Patients with hypothyroidism at base line and patients who are not been treated with curative intent.

Design outcomes

Primary

MeasureTime frame
incidence of radiation induced hypothyroidismTimepoint: At base line and one year after completion of radiotherapy

Secondary

MeasureTime frame
To identify risk factors for radiation induced hypothyroidism Timepoint: At base line and one year after completion of radiotherapy

Countries

India

Contacts

Public ContactSiddharth Vats

IGMC Shimla

drsiddharthvats@gmail.com9418458100

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026