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To differentiate the features of two different drugs named as Nalbuphine and Buprenorphine when given along with Heavy Bupivacaine in the spinal route in planned surgical patients

A Comparative Study on Effect of Intrathecal Nalbuphine and Buprenorphine when added as an Adjuvant to 0.5% Hyperbaric Bupivacaine in Elective Infraumbilical surgeries - -

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/05/033520
Enrollment
106
Registered
2021-05-10
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 3- Administration Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Sensory, motor blockade, haemodynamics and postoperative analgesia: Baseline,1,5,10,15,30,60 and 90 minutes Control Intervention1: Comparing Nalbuphine and Buprenorphine with 0.5% Hyper

Sponsors

Sandhya K
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients acceptance 2.Patients aged above 20 and below 65 years 3.ASA status I and II patients 4.Patients undergoing elective infraumbilical surgeries under spinal anaesthesia 5.Surgeries involving lower abdomen, urological, gynaecological, orthopaedic and lower limb extremity

Exclusion criteria

Exclusion criteria: 1.Patient denial 2.Absolute contraindications for spinal anaesthesia 3.Combined spinal epidural anaesthesia 4.Known hypersensitivity or allergy to study drugs 5.Pregnancy and lactating mothers 6.Morbid obesity (BMI >40) 7.Age below 20 years 8.Infection at the site of sub arachnoid block 9.Bleeding and coagulation disorders

Design outcomes

Primary

MeasureTime frame
Primary Objective is to study the objectives of onset, duration of sensory and motor blockade intraoperatively.Timepoint: 1,3,5,10,15,30,60,90,120,180 minutes—

Secondary

MeasureTime frame
Secondary objective is to compare the haemodynamics between the groups intraoperatively, duration of post-operative analgesia and their side effects encountered.Timepoint: 1,3,5,10,15,30,60,90,120,180 minutes—

Countries

India

Contacts

Public ContactR Arun Kumar

PSG Institute of Medical Sciences and Research

sandhyakandasamy@gmail.com04222570170

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026