Health Condition 1: P041- Newborn affected by other maternalmedication
Conditions
Interventions
Intervention1: Antenatal Dexamethasone: Women who receive at least one dose of injection dexamethasone in the late preterm period (34 weeks to 36 6/7 weeks gestation) between 7 days before delivery an
Sponsors
Institute of Post Graduate Medical Education and Research Department of Neonatology
Eligibility
Inclusion criteria
Inclusion criteria: 1.Women with singleton pregnancy presenting between 34 weeks -36 6/7 weeks of gestation who are likely to deliver within next 7 days. Indicators of delivery within next 7 days are the presence of true labor pain, antepartum hemorrhage, preterm premature rupture of membrane, severe pre-eclampsia and evidence of fetal distress. 2.Women with singleton pregnancy admitted between 34 weeks -36 6/7 weeks of gestation for scheduled caesarian section.
Exclusion criteria
Exclusion criteria: 1.Presence of clinical chorioamnionitis 2. Presence of multiple pregnancy 3. If the woman had already received antenatal steroid before study enrollment 4. Absence of the first trimester dating scan or unsure about the date of last menstrual period 5.Presence of major congenital anomaly, chromosomal anomaly or surgical conditions either diagnosed antenatally or detected postnatally 6.Family history or presence of congenital hyperinsulinism , metabolic disorder, or Beckwith -Wiedemann syndrome in the newborn
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Neonatal hypoglycemia which will be defined as a whole blood glucose level of 40 mg/dL2. For screening purpose initial blood glucose will be measured from capillary blood with a point of care glucometer. Any CBG value 40 mg/dL will be confirmed by whole blood glucose value.Timepoint: 1.At 2 hours of life 2.At 6 hours of life 3.At 12 hours of life 4.At 24 hours of life 5.At 48 hours of life 6.At 72 hours of life | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Symptomatic hypoglycaemia 2.Duration of hypoglycemia 3.Respiratory distress syndrome 4.Transient tachypnea of the newborn 5.Apnea 6.Hemodynamically significant Patent ductus arteriosus 7.Intraventricular hemorrhage 8.Necrotizing enterocolitis 9.Bronchopulmonary dysplasia 10. requirement of respiratory support and duration 11. Requirement of surfactant 12.Hospital stay Timepoint: 1. At discharge from hospital | — |
Countries
India
Contacts
Public ContactSomnath Pal
Institute of Post Graduate Medical Education and Research
Outcome results
None listed