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ROLE OF MAGNESIUM SULPHATE IN PREVENTION OF POSTOPERATIVE PAIN IN LAPAROSCOPIC GALL BLADDER SURGERY

EFFECTIVENESS OF INTRAPERITONEAL MAGNESIUM SULPHATE IN PREVENTION OF POSTOPERATIVE PAIN IN ELECTIVE LAPAROSCOPIC CHOLECYSTECTOMY: A PROSPECTIVE RANDOMISED CONTROLLED TRIAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/05/033417
Enrollment
64
Registered
2021-05-06
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K80-K87- Disorders of gallbladder, biliary tract and pancreas

Interventions

Intervention1: 50mg/kg of 10% MgSO4 diluted in 100 ml 0.9% normal saline: 50mg/kg of 10% MgSO4 diluted in 100 ml 0.9% normal saline will be instilled in the subdiaphragmatic space over 20 minutes afte

Sponsors

PGIMER CHANDIGARH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ) Any gender 2) 18 – 65 years of age 3) ASA-I and II patients

Exclusion criteria

Exclusion criteria: Patient refusal to participate in the study 2) Conversion to open cholecystectomy 3) Pre-existing neurological or psychiatric illness which precludes giving an informed consent 4) Pre-existing active cardiac or renal impairment ( Creatinine level > 1.5 times of normal value ) and chronic disease.

Design outcomes

Primary

MeasureTime frame
1)To evaluate the analgesic efficacy of intraperitoneal magnesium sulphate in the prevention of postoperative pain in first 24 hours after surgery among patients undergoing elective laparoscopic cholecystectomyTimepoint: start of surgery to 48 hours after surgery

Secondary

MeasureTime frame
1) To observe the incidence of postoperative pain 2) To evaluate requirement of total dose of analgesic after surgery 3) To observe the incidence of postoperative nausea and vomiting 4) To observe the effect on emergence time 5) To observe any postoperative adverse events related to magnesium sulfate Timepoint: start of surgery to 48 hours after surgery

Countries

India

Contacts

Public ContactDivya dahiya

PGIMERChandigarh

dahiyadivya@yahoo.com8901027425

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026