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Effect of Homatropine in eyes with Fresh Vitreous Haemorrhage

Comparison of effect of Homatropine, Head elevation and Observation in Fresh Vitreous Haemorrhage using Quantitative Ophthalmic Ultrasonography

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/05/033400
Enrollment
60
Registered
2021-05-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H431- Vitreous hemorrhage

Interventions

Intervention1: Eye drops Homatropine 2%: Topical 2% homatropine eye drops solution 3 times a day for 21 days Control Intervention1: Head Elevation: Sleep with two standard size pillows so as to kee

Sponsors

AIIMS Bathinda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Best corrected visual acuity (BCVA) HMCF to 6/12 and plan to conservatively manage VH.Fresh Vitreous Haemorrhage will be defined as Clinically diagnosed, first time spontaneous VH dense enough to obscure some part of the retina, with duration of less than 2 weeks of onset.

Exclusion criteria

Exclusion criteria: Recurrent VH, VH with ultrasonic evidence of retinal tears or rhegmatogenous retinal detachment or tumour, previous treatment with intravitreal drugs, trauma, intraocular surgery within one month,advanced cataract precluding examination of posterior segment, neovascularisation of the iris (NVA)or angle (NVA), glaucoma or high IOP,systemic diseases limiting patientâ??s ability to be complaint with positioning, h/o allergy to homatropine E/ds

Design outcomes

Primary

MeasureTime frame
Primary objective is change in BCVA at end of study period.Timepoint: Participants in all groups will be examined in a similar fashion on Day 1,3,7,15 and 21 days for a period of 3 weeks

Secondary

MeasureTime frame
Secondarily resolution of VH will also be assessed using VH grading scalesTimepoint: Participants in all groups will be examined in a similar fashion on Day 1,3,7,15 and 21 days for a period of 3 weeks

Countries

India

Contacts

Public ContactDr Sanjeev Kumar

AIIMS, Bathinda

globuseye@gmail.com9803030167

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026