Health Condition 1: M179- Osteoarthritis of knee, unspecified
Conditions
Interventions
Intervention1: Intraarticular injection of platelet rich plasma. Group II patients will be administered 6 ml of PRP prepared by collecting 20 ml of patients blood running it through a centrifuge for 1
Sponsors
Pt BD Sharma PGIMS Rohtak
Eligibility
Inclusion criteria
Inclusion criteria: Fifty patients of either sex, age more than 50 years, attending Pain Clinic and fulfilling following three criteria will be included in the study: History, physical examination and pain pattern consistent with osteoarthritis of knee X-ray knee joint findings corresponding with the patient’s clinical symptoms Failure to respond to six weeks of conservative treatment.
Exclusion criteria
Exclusion criteria: Patients with History of uncontrolled diabetes mellitus History of immunodeficiency, collagen vascular disorders or autoimmune disorders Infection or active wound in the knee area Recent history of severe trauma to the knee or knee surgery History of treatment with anticoagulants and antiplatelet drugs 10 days before injection History of NSAID use two days before injection History of intra-articular steroid injection in the past three months History of systemic use of steroid two weeks before the injection Hb values History of adverse drug reaction to local anesthetics or steroids
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of pain using pain scoreTimepoint: Half hour before procedure Half hour after procedure 2 weeks after procedure 1 month after procedure 2 months after procedure 3 months after procedure | — |
Secondary
| Measure | Time frame |
|---|---|
| The Western Ontario and McMaster Universities (WOMAC) Index of OsteoarthritisTimepoint: The WOMAC Index will be calculated half hour before the procedure; two weeks, one month, two months and three months after the procedure.;Patient satisfaction Timepoint: Patient satisfaction will be assessed two weeks, one month, two months and three months after the procedure. | — |
Countries
India
Contacts
Public ContactDr Aditi
Pt B.D. Sharma ,PGIMS,Rohtak
Outcome results
None listed