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Evaluation of drugs fentanyl and bupivacaine in spinal anaesthesia when given mixed together and when fentanyl and bupivacaine are given separately for lower limb tibial surgeries

Efficacy of premixed versus sequential administration of fentanyl and bupivacaine in subarachnoid block for lower limb tibial surgeries: A randomised control study

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/04/033259
Enrollment
90
Registered
2021-04-30
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Spinal Anaesthesia: Sequential administration of Inj Fentanyl and Inj Bupivacaine Heavy Intervention2: Spinal anaesthesia given using single syringe: Intrathecally premixed Inj fentany

Sponsors

Government medical college Vadodara
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA - I/II/III

Exclusion criteria

Exclusion criteria: Patients with absolute and relative contraindications to spinal anaesthesia(Patient refusal,Local skin infection, Vertebral column abnormalities, bleeding disorders, cardiopulmonary disease, neuropathies). Patients with allergy to local anaesthetics Pregnant and lactating females

Design outcomes

Primary

MeasureTime frame
-Sensory and Motor blockade characteristics -To observe any changes in hemodynamic parameters likepulse rate, blood pressure, respiratory rate, ECG, SpO2 perioperativelyTimepoint: Time from administration of drug intrathecally till 24 hours.

Secondary

MeasureTime frame
-Duration of effective analgesia -To observe any complications like bradycardia, hypotension, respiratory depression, shivering, nausea vomiting, pruritus, dryness of mouth, urinary retentionTimepoint: time from administration of drug intrathecally till 24 hours.

Countries

India

Contacts

Public ContactDr Apeksha Patwa

Government medical college, Vadodara

patwaapeksha@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026