Health Condition 1: K639- Disease of intestine, unspecified Health Condition 2: K57- Diverticular disease of intestine Health Condition 3: K60- Fissure and fistula of anal and rectal regions Health Condition 4: K591- Functional diarrhea Health Condition 5: K64- Hemorrhoids and perianal venous thrombosis Health Condition 6: K580- Irritable bowel syndrome with diarrhea Health Condition 7: K589- Irritable bowel syndrome without diarrhea Health Condition 8: K50-K52- Noninfective enteritis and coliti
Conditions
Interventions
Intervention1: 2-L Polyethylene Glycol Solution with Prucalopride: Patient should be on low fiber diet for 3days preceding colonoscopy. Split-dose regimen will be used for the prucalopride and PEG gro
Sponsors
Manjit Kanungo
Eligibility
Inclusion criteria
Inclusion criteria: Adult (>=18 years) patients scheduled for colonoscopy will be recruited from the outpatient department of gastroenterology, Andhra medical college, Visakhapatnam.
Exclusion criteria
Exclusion criteria: 1. Known or suspected bowel obstruction or perforation 2. Acute exacerbation of inflammatory bowel disease 3. Toxic megacolon 4. History of colorectal resection 5. Compromised swallowing reflex or mental status 6. Significant gastroparesis or gastric outlet obstruction 7. Severe congestive heart failure (NYHA III/IV), recent acute MI or unstable angina (within 8 weeks) 8. Severe chronic renal failure (creatinine clearance 9. Pregnancy or lactation 10.H/O of hypersensitivity to any bowel cleansing agent 11.Chronic constipation ( week with or without laxative)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy of bowel preparationTimepoint: Proportion of patients having adequate bowel preparation will be assessed during colonoscopy by using Boston Bowel Preparation Scale (BBPS). Adequate bowel preparation will be defined as a total BBPS score â?¥6 and each segment scores â?¥ 2. | — |
Secondary
| Measure | Time frame |
|---|---|
| Patientâ??s compliance and acceptabilityTimepoint: Compliance will be scored on a 3-grade scale according to the percentage of total solution intake (â?¥ 75% will be considered as adequate). Acceptability will be assessed by easiness of bowel preparation intake and percentage of patients willing to repeat it in future if needed .;Patientâ??s safetyTimepoint: Safety will be assessed by occurrence of new or increase in severity of preexisting gastrointestinal symptoms after bowel preparation intake. | — |
Countries
India
Contacts
Public ContactManjit Kanungo
Department of Gastroenterology, Andhra Medical College
Outcome results
None listed