early inducing labour in women whose amniotic fluid leaked before the on set of labour vs waiting for some time and induction of labour, because that waiting period there is chance to progress spontaneously here oral misoprostol tablet is used for inducing

Early vs late induction with oral misoprostol in pre labour rupture of membranes: A Randomized controlled trial

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/04/033187

Enrollment

Registered

2021-04-28

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O758- Other specified complications of labor and delivery

Interventions

Intervention1: oral misoprostol: Group A: Whenever a Term PROM patient with leaking PV for less than 6 hours , with BISHOP score Less than 6 is admitted in the hospital, she will be induced with oral

Eligibility

Inclusion criteria

Inclusion criteria: Pregnant women with gestational age greater than or equal to 37weeks to 42weeks,membranes ruptured, modified BISHOP score <6,Live fetus, singleton pregnancy, cephalic presentation.

Exclusion criteria

Exclusion criteria: premature prelabour rupture of membranes, multifetal gestation, non cephalic presentation, previous uterine scar and uterine rupture, antepartum hemorrhage, fetal anomalies, active genital herpes, pelvic structural deformities associated with cephalopelvic disproportions, invasive cervical carcinoma, previous pelvic surgeries

Design outcomes

Primary

Measure	Time frame
To compare the induction to delivery interval in both groups 12-24 hoursTimepoint: To compare the induction to delivery interval in both groups 12-24 hours	—

Secondary

Measure	Time frame
to compare the mode of delivery in both the groups. to compare fetal and maternal outcomes Timepoint: rupture of membranes, time of delivery and postnatal period in mother and neonatal period in baby	—

Countries

India

Contacts

Public ContactDr Deepthy Balakrishnan

AIIMS,Bhubaneswar

balakrishnandeepthy@gmail.com9446439373

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026