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A clinical trial to study the effects of coffee and chewing gum on return of normal bowel function after undergoing surgery for malignant tumors of female reproductive system.

Effect of drinking coffee and gum chewing on postoperative bowel activity after gynecological oncosurgeries: A randomized controlled trial - CHEWCOFF study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/04/033141
Enrollment
180
Registered
2021-04-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C539- Malignant neoplasm of cervix uteri, unspecified Health Condition 2: C549- Malignant neoplasm of corpus uteri, unspecified Health Condition 3: C530- Malignant neoplasm of endocervix Health Condition 4: C541- Malignant neoplasm of endometrium Health Condition 5: C531- Malignant neoplasm of exocervix Health Condition 6: C543- Malignant neoplasm of fundus uteri Health Condition 7: C540- Malignant neoplasm of isthmus uteri Health Condition 8: C562- Malignant neoplasm of left

Interventions

Intervention1: Chewing gum: sugarless chewing gums to chew 3 times daily at 15:00, 19:00, and, 10.00 hours until initiation of solid diet or, for 2 days whichever is earlier, starting from the day of

Sponsors

JIPMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Those who are scheduled for abdominal surgery for clinical diagnosis of any gynecological malignancy

Exclusion criteria

Exclusion criteria: Pre-operative 1. Caffeine/coffee intolerance 2. Thyroid disorder/ Cardiac dysrrythmia 3. History of (H/O) diseases such as persistent diarrhea, chronic constipation, irritable bowel syndrome, inflammatory bowel disease, and/or, co-existing gut motility disorder 4. Prior H/O bowel surgery(s) 5. Prior H/O pelvic/ abdominal irradiation Intra-operative 6. Operative duration > 4 hours 7. Intra-peritoneal chemotherapy given 8. Intra-operative bowel injury/ bowel anastomoses 9. Upper abdominal multi-visceral surgical debulking approach Post-operative 10. ICU admission > 48 hours 11. Nasogastric tube in situ on 1st post-operative day. 12. Histopathology suggesting benign disease

Design outcomes

Primary

MeasureTime frame
The time interval in hours between skin closure of surgery to first solid oral feedTimepoint: time when the patient takes first oral feed after surgery for first time

Secondary

MeasureTime frame
Interval between skin closure of surgery to first appearance of intestinal peristaltic soundTimepoint: every 4hour till bowel sound is heard;Interval between skin closure of surgery to first defecationTimepoint: time when patient defecates after surgery first time;Mean duration of hospital stayTimepoint: at discharge from hospital

Countries

India

Contacts

Public ContactSunabha Kumar Ghosh

JIPMER, Puducherry

drsasirekha.r_ms@ymail.com9786111445

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026