To compare requirement of first dose of pain killer when two different drugs are used as supplement for fascia iliaca compartment block

Comparative evaluation of duration of first rescue analgesia in fascia iliaca compartment block with dexamethasone or dexmedetomidine after femur fracture surgeries

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/04/033134

Enrollment

Registered

2021-04-27

Start date

Unknown

Completion date

Unknown

Last updated

2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: S723- Fracture of shaft of femur Health Condition 3: O- Medical and Surgical

Interventions

Intervention1: Bupivacaine with dexmedetomidine: Patients will receive 40 ml of a solution (38 ml of 0.25% Bupivacaine and 0.5 mcg/kg dexmedetomidine in 2ml normal saline) Control Intervention1: Bupiv

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologist physical status one and two BMI more than equal to 20 to less than equal to 30kg/m2 Patients scheduled for neck and shaft of femur fracture surgery

Exclusion criteria

Exclusion criteria: Patientâ??s inability to understand VAS Patients scheduled for multiple fracture surgeries Patients with coagulopathy and bleeding disorders Pre-existing peripheral neuropathy Patients on regular chronic pain management drugs for the last three months Pregnant and lactating women Contraindications to study drugs Paracetamol diclofenac dexamethasone dexmedetomidine and bupivacaine

Design outcomes

Primary

Measure	Time frame
To compare the duration of first rescue analgesia in patients receiving FICB with dexamethasone or dexmedetomidine as adjuvants to 0.25% bupivacaine following femur surgeryTimepoint: Within 24 hours	—

Secondary

Measure	Time frame
Any other complaintTimepoint: 0 minute 5 minutes 10 minutes 15 minutes 60 minutes 2 hours 4 hours 6 hours 8 hours 12 hours 24 hours;Bloop PressureTimepoint: 0 minute 5 minutes 10 minutes 15 minutes 60 minutes 2 hours 4 hours 6 hours 8 hours 12 hours 24 hours;Nausea/ vomitingTimepoint: 0 minute 5 minutes 10 minutes 15 minutes 60 minutes 2 hours 4 hours 6 hours 8 hours 12 hours 24 hours;Patient Satisfaction ScoreTimepoint: 0 minute 5 minutes 10 minutes 15 minutes 60 minutes 2 hours 4 hours 6 hours 8 hours 12 hours 24 hours;Pulse RateTimepoint: 0 minute 5 minutes 10 minutes 15 minutes 60 minutes 2 hours 4 hours 6 hours 8 hours 12 hours 24 hours;Respiratory RateTimepoint: 0 minute 5 minutes 10 minutes 15 minutes 60 minutes 2 hours 4 hours 6 hours 8 hours 12 hours 24 hours;Total rescue analgesic doseTimepoint: Within 24 hours;VAS at movementTimepoint: 0 minute 5 minutes 10 minutes 15 minutes 60 minutes 2 hours 4 hours 6 hours 8 hours 12 hours 24 hours;VAS at restTimepoint: 0 minute 5 minutes 10 minutes 15 minutes 60 minutes 2 hours 4 hours 6 hours 8 hours 12 hours 24 hours	—

Measure

Time frame

Any other complaintTimepoint: 0 minute 5 minutes 10 minutes 15 minutes 60 minutes 2 hours 4 hours 6 hours 8 hours 12 hours 24 hours;Bloop PressureTimepoint: 0 minute 5 minutes 10 minutes 15 minutes 60 minutes 2 hours 4 hours 6 hours 8 hours 12 hours 24 hours;Nausea/ vomitingTimepoint: 0 minute 5 minutes 10 minutes 15 minutes 60 minutes 2 hours 4 hours 6 hours 8 hours 12 hours 24 hours;Patient Satisfaction ScoreTimepoint: 0 minute 5 minutes 10 minutes 15 minutes 60 minutes 2 hours 4 hours 6 hours 8 hours 12 hours 24 hours;Pulse RateTimepoint: 0 minute 5 minutes 10 minutes 15 minutes 60 minutes 2 hours 4 hours 6 hours 8 hours 12 hours 24 hours;Respiratory RateTimepoint: 0 minute 5 minutes 10 minutes 15 minutes 60 minutes 2 hours 4 hours 6 hours 8 hours 12 hours 24 hours;Total rescue analgesic doseTimepoint: Within 24 hours;VAS at movementTimepoint: 0 minute 5 minutes 10 minutes 15 minutes 60 minutes 2 hours 4 hours 6 hours 8 hours 12 hours 24 hours;VAS at restTimepoint: 0 minute 5 minutes 10 minutes 15 minutes 60 minutes 2 hours 4 hours 6 hours 8 hours 12 hours 24 hours

—

Countries

India

Contacts

Public ContactDr Disha Lodha

Government Medical College and Hospital, Sector 32, Chandigarh

dpkthapa@gmail.com9646121524

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026