FindTrial
Sign In

A COMPARISON OF POST-OPERATIVE ANALGESIC EFFICACY OF OPIOID FREE ANAESTHESIA USING INTRAVENOUS PARACETAMOL, LIGNOCAINE AND MAGNESIUM SULFHATE VERSUS STANDARD OPIOID ANAESTHESIA USING INTRAVENOUS TRAMADOL FOR PREEMPTIVE ANALGESIA IN ABDOMINAL SURGERIES UNDER GENERAL ANAESTHESIA

A COMPARISON OF EFFICACY OF OPIOID FREE ANAESTHESIA USING INTRAVENOUS PARACETAMOL(15MG/KG) VERSUS STANDARD OPIOID ANAESTHESIA USING INTRAVENOUS TRAMADOL(2MG/KG) IN ABDOMINAL SURGERIES UNDER GENERAL ANAESTHESIA

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/04/033097
Enrollment
60
Registered
2021-04-26
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Opioid free versus standard opioid anaesthesia: Group A Case (OFA group) Opioid free anesthesia (OFA) - Injection Lignocaine (2mg/kg)+ Injection MgSO4 (2gm/8mmol) + Injection Paracetamo

Sponsors

JLN medical college Ajmer
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients posted for elective Abdominal surgery under general anaesthesia. Age between 18 to 65 years. ASA physical status 1 and 2

Exclusion criteria

Exclusion criteria: Pregnant or Breastfeeding women Emergency surgery Patients refusal. Patient sensitive / allergic to any of the study drugs. Patients with neuro-psychiatric illness. Cardiovascular disease patients (1 and 2 degree heart block) Patients on beta blockers. Severe bradycardia (HR Severe hepatic and renal disease.

Design outcomes

Primary

MeasureTime frame
The primary outcome of our study will be the 24hour post-operative analgesic consumption in both the groupsTimepoint: Outcome will be assessed at 0hr, 2hr, 4hr, 6hr, 8hr, 12hr, 16hr, 20hr and 24hr postoperatively.—

Secondary

MeasureTime frame
Quality of analgesia using( NRS) Duration of post-operative analgesia Effect on hemodynamic parameters intraoperatively. Stress response to laryngoscopy at the time of intubation. Recovery time (Aldrete score 9) QoR-15 (post- operative patient comfort) Sedation (Ramsay sedation score) Post operative nausea vomiting Complications like pruritus, respiratory distress, sedation, bradycardia, hypotension.Timepoint: Outcomes will be assessed intraoperatively at baseline, 1, 2, 3, 5, 15, 30, 45, 60, 75, 90, 105, 120, 135 and 150 minutes. Postoperatively outcomes will be assessed at 0hr, 2hr, 4hr, 6hr, 8hr, 12hr, 16hr, 20hr and 24hr—

Countries

India

Contacts

Public ContactDr Neena Jain

JLN medical college, Ajmer

drneenaj@gmail.com9414008666

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026