Comparative study of long term versus short term use of octreotide drug to decrease fluid collection post breast surgery

Comparison of short term versus long term Octreotide for reduction of lymphorrhoea following modified radical mastectomy-A randomised study

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/04/033075

Enrollment

Registered

2021-04-23

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: Short term use of octreotide to reduce lymphorrhoea post modified radical mastectomy: Administration of Inj Octreotide 100mg intravenously TDS , for 48 hours post modified radical maste

Eligibility

Inclusion criteria

Inclusion criteria: All patients of carcinoma breast, above 18 years of age, planned for modified radical mastectomy

Exclusion criteria

Exclusion criteria: 1. Previous irradiation to chest 2. Known hypersensitivity to octreotide 3. History of cardiovascular disease, renal and hepatic impairment 4. Pregnancy and lactation

Design outcomes

Primary

Measure	Time frame
Decrease in lymphorrhoea (drain output) volumeTimepoint: Assessed everyday starting from post operative day 1 till drain removal	—

Secondary

Measure	Time frame
1. Surgical site infection 2. Incidence of seroma formationTimepoint: Follow up for 1 month	—

Countries

India

Contacts

Public ContactDr Sushanto Neogi

Maulana Azad medical college

sushantoneogi@gmail.com9968604384

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026