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a study to know if the leaf extracts could prolong the life of a filling in the patients mouth.

Evaluating the Effect of Two Herbal Extracts in inhibiting Endogenous Matrix Metalloproteinase (MMP) Activity and Enhancing the Dentin Bond Durability – A Randomised Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/04/033069
Enrollment
100
Registered
2021-04-23
Start date
Unknown
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K025- Dental caries on pit and fissure surface

Interventions

Intervention1: Moringa Oleifera: In a tooth preparation, after etching, the leaf extract will be applied on Dentin for 5 sec, dried and later the bonding agent will be applied. followed by composite r

Sponsors

Lavanya Anumula
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with a minimum of two caries lesions, ICDAS score 4,5,6 With no known allergies

Exclusion criteria

Exclusion criteria: Teeth that are periodontally compromised, Teeth that may require vital pulp therapy

Design outcomes

Primary

MeasureTime frame
Stability of the dentin bond (Hybrid layer) measured by Clinical Success of the restorationTimepoint: 6 months and 12 months—

Secondary

MeasureTime frame
Evaluation by FDI criteria – Esthetic, Functional and Biological PropertiesTimepoint: 6 months and 1 year—

Countries

India

Contacts

Public ContactDr K V Suneel Kumar

Saveetha Dental College and Hospital

drsinsushil@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026