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Differentiate and assess the effectiveness of locally delivered 1.2% Rosuvastatin gel and tetracycline fibre as a treatment of Periodontitis.

Comparative evaluation of efficacy of locally delivered 1.2% Rosuvastatin gel and tetracycline fibre as a treatment of Stage II & III periodontitis Grade A- A randomised controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/04/033057
Enrollment
75
Registered
2021-04-23
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: 1.2% ROSUVASTATIN GEL: ROSUVASTATIN IS A SECOND GENERATION SULPHUR CONTAINING, SYNTHETIC, HYDROPHILLIC STATIN WHICH HAS POTENT ANTIINFLAMMATORY ACTION AND ITS INTAKE AS LOCAL APPLICATIO

Sponsors

DR AASTHA DEBNATH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)SYSTEMICALLY HEALTHY PARTICIPANTS DIAGNOSED WITH LOCALIZED OR GENERALIZED STAGE II/III PERIODONTITIS22 WITHIN THE AGE GROUP OF 30-60 YEARS. 2)PARTICIPANTS WITH AT LEAST THREE NONADJACENT SITES WITH 5-7 MM OF PROBING POCKET DEPTH (PPD) WITH NO CONTRAINDICATION TO PERIODONTAL THERAPY. 3)PARTICIPANTS SHOULD NOT HAVE RECEIVED ANY ANTIBIOTIC AND PERIODONTAL THERAPY FOR PAST 6 MONTHS

Exclusion criteria

Exclusion criteria: 1)PATIENT WITH HABIT OF TOBACCO CHEWING AND SMOKING. 2)PARTICIPANTS WHO ARE PREGNANT AND LACTATING WOMEN 3)PATIENTS USING ANTI-MICROBIAL MOUTHWASH IN THE PAST 2 MONTHS 4)PARTICIPANTS WITH ALLERGY TO STATINS/TETRACYCLINE.

Design outcomes

Primary

MeasureTime frame
1)PLAQUE INDEX 2)PROBING DEPTH 5MM 3)RELATIVE ATTACHMENT LEVEL 4)BLEEDING INDEX 5)GINGIVAL MARGIN POSITION 6)INTRABONY DEFECT Timepoint: AT BASELINE AT 3 MONTHS AT 6 MONTHS—

Secondary

MeasureTime frame
1)PLAQUE INDEX 2)PROBING DEPTH 5MM 3)RELATIVE ATTACHMENT LEVEL 4)BLEEDING INDEX 5)GINGIVAL MARGIN POSITION 6)INTRABONY DEFECT Timepoint: BASLINE TO 6 MONTHS—

Countries

India

Contacts

Public ContactDR MONALI SHAH

K M SHAH DENTAL COLLEGE & HOSPITAL

hod_periodontics@sumandeepvidyapeethdu.edu.in9824003228

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026