Skip to content

A clinical study to assess the effect of drug magnesium sulphate to reduce blood loss in sinus surgery.

EVALUATION OF EFFICACY OF MAGNESIUM SULPHATE IN REDUCING BLOOD LOSS IN FUNCTIONAL ENDOSCOPIC SINUS SURGERY- A RANDOMIZED DOUBLE-BLINDED CONTROLLED TRIAL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/04/033052
Enrollment
60
Registered
2021-04-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Magnesium sulphate: 50mg/kg bolus Control Intervention1: Normal saline: 10ml

Sponsors

SRM medical college hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: FESS Surgeries for chronic rhinosinusitis, sinonasal polyposis Patients under ASA 1 and 2 BMI between 18.5 to 24.99

Exclusion criteria

Exclusion criteria: Hypermagnesemia(on routine pre anaesthetic biochemical screening) Patients with any degree of heart block, cardiovascular or renal disease, or a coagulation disorder

Design outcomes

Primary

MeasureTime frame
To study the blood loss reduction with magnesium sulphate in functional endoscopic sinus surgeryTimepoint: Calculated at the end of surgery

Secondary

MeasureTime frame
1)Intra operative additional requirement of fentanyl 2) Stress attenuation during laryngoscopy and endotracheal intubation 3)time for extubation Timepoint: 1)Requirement of additional fentanyl 0.5mcg/kg if heart rate/systolic blood pressure increases more than 20%. 2)heart rate and mean arterial pressure intraoperatively will be measured. 3)17. Time taken from completion of surgical dressing to removal of endotracheal tube will be taken as time for extubation and is noted.

Countries

India

Contacts

Public ContactRajagopalan Venkatraman

srm Medical College Hospital and Research

drvenkat94@gmail.com09894581455

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 9, 2026