Health Condition 1: D561- Beta thalassemia
Conditions
Interventions
None listed
Sponsors
Kasturba Medical College
Eligibility
Inclusion criteria
Inclusion criteria: Children diagnosed to have Beta Thalassemia major on regular blood transfusion between the age group 5-18 years admitted in the Department of Paediatrics Kasturba Medical College ,Manipal will be included
Exclusion criteria
Exclusion criteria: Children with Beta Thalassemia and diagnosed with any other liver pathology such as : 1.Hepatitis B,C,Wilsons Disease ,Autoimmune hepatitis 2.Obese children 3.Fatty liver will be excluded .
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of liver fibrosis using Fibroscan and finding a co-relation with serum ferritin levels,serum transaminases,iron chelation therapy and yearly transfusion requirement in thalassemia children .Timepoint: Assessment of liver fibrosis using Fibroscan and finding a co-relation with serum ferritin levels,serum transaminases,iron chelation therapy and yearly transfusion requirement in thalassemia children and comparing the findings with a repeat Fibroscan after one year. | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessment of liver fibrosis using Fibroscan and finding a co-relation with serum ferritin levels,serum transaminases,iron chelation therapy and yearly transfusion requirement in thalassemia children and comparing the findings with a repeat Fibroscan after one year.Timepoint: The findings will be compared with a repeat Fibroscan after one year. | — |
Countries
India
Contacts
Public ContactDr Koushik H
Kasturba Medical College Manipal.
Outcome results
None listed