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Does giving oxygen to patients through nasal tube before giving artificial respiration (intubation) improve oxygen level in patients with respiratory failure compared to the standard face mask oxygen in patients presenting to Emergency Department.

Does pre-oxygenation with a nasopharyngeal cannula during intubation improve the apneic oxygenation of patients with acute hypoxemic respiratory failure compared to the standard Bag valve mask pre-oxygenation in patients presenting to Emergency department.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/04/032993
Enrollment
76
Registered
2021-04-22
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J960- Acute respiratory failure

Interventions

Intervention1: Pre-oxygenation with nasopharyngeal cannula in additition standard care: patients presenting to emergency department with acute hypoxemic respiratory failure requiring intubation will r

Sponsors

Christain medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with acute hypoxemic respiratory failure defined as hypoxemia PaO2 <60 or with 20% drop in saturation from baseline with indication for intubation

Exclusion criteria

Exclusion criteria: 1.Those not consenting for the study 2.Pregnancy 3.Contraindication to nasopharyngeal cannula like nasopharyngeal obstruction or blockage, nasal bone fractures, basilar skull fracture 4.Difficult airway due to reduced neck movement, mouth opening, Mallampatti score of class >2.

Design outcomes

Primary

MeasureTime frame
Median lowest Spo2 during intubation between the interventional and control arm Mortality during emergency stay Timepoint: zero,immediate and thirty minutes post intubation—

Secondary

MeasureTime frame
Difference in respiratory, hemodynamic parameters and incidence of adverse events post intubationTimepoint: zero to thirty minutes post intubation—

Countries

India

Contacts

Public ContactIrfan zubair S

Christain medical college ,Vellore

priyajyotsnav@gmail.com8903308084

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026