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Clinical trial comparing effects of Anaesthetic induction agents on Heart Function

COMPARISON OF EFFECTS OF GENERAL ANAESTHESIA INDUCTION WITH THIOPENTONE-FENTANYL AND PROPOFOL-FENTANYL COMBINATIONS ON LEFT VENTRICULAR FUNCTION ASSESSED BY TRANSTHORACIC ECHOCARDIOGRAPHY: A ONE YEAR RANDOMISED CLINICAL TRIAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/04/032962
Enrollment
60
Registered
2021-04-20
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring

Interventions

Control Intervention1: Propofol-Fentanyl: Inj. Propofol 2mg/kg IV Bolus Inj. Fentanyl 2 mcg/kg IV Bolus Both given as part of GA induction and their effect on Left Ventricular Function measured with

Sponsors

KLEs JN Medical College and Dr Prabhakar Kore Charitable Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologists physical status I and II. Age between 18 to 60 years. Patients undergoing elective surgeries under general anaesthesia. Provides Consent

Exclusion criteria

Exclusion criteria: Patient undergoing emergency surgery. Patient who are unable or unwilling to give consent. Patients who do not fulfil inclusion criteria. Pre-existing cardiac diseases (Ischaemic Heart Disease, valvular and congenital heart diseases) Pregnant Females

Design outcomes

Primary

MeasureTime frame
TO ASSESS THE EFFECTS OF THIOPENTONE-FENTANYL VS. PROPOFOL-FENTANYL ON LEFT VENTRICULAR SYSTOLIC FUNCTION IN PATIENTS UNDERGOING NON-CARDIAC SURGERIES UNDER GENERAL ANAESTHESIA USING TRANS-THORACIC ECHOCARDIOGRAPHYTimepoint: Pre-Operative 3 minutes post induction of anaesthesia

Secondary

MeasureTime frame
There is No Secondary ObjectiveTimepoint: There is No Secondary Objective

Countries

India

Contacts

Public ContactRohit Bohra

Department of Anaesthesiology KLEs JN Medical College and Dr Prabhakar Kore Charitable Hospital

mcpatil52@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026