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Comparison of Relief of pain on injection of propofol which is a commonly used drug for inducing anaesthesia, by application of ice gel pack over the cannula which will be used to inject propofol versus giving lignocaine which is a local anaesthetic prior to propofol

Prevention of Pain on Injection of Propofol using Ice Gel Pack vs Pre-treatment with Lignocaine: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/04/032950
Enrollment
200
Registered
2021-04-20
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: ICE PACK THERAPY: Application of an ice-cooled gel pack proximal to the intravenous cannula for a duration of 2 minutes. Control Intervention1: LIGNOCAINE: 0.5MG/KG OF LIGNOCAINE WILL

Sponsors

Postgraduate Institute of Medical Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age 18-65 years 2. ASA I, II & III 3. Elective/ emergency Surgeries 4. Undergoing general anesthesia

Exclusion criteria

Exclusion criteria: 1. Allergy to any of the drugs being used 2. Rapid Sequence Induction 3. Anticipated difficulty in venous access 4. Contraindications to use of propofol/ lignocaine 5. Chronic pain 6. Diabetic Neuropathy

Design outcomes

Primary

MeasureTime frame
To compare the overall incidence of pain as well as the occurrence of various grades of pain after propofol injection, following the application of ice gel pack causing local cooling and pretreatment with lignocaine intravenouslyTimepoint: At the time of injection of propofol

Secondary

MeasureTime frame
To assess the incidence of discomfort to the patients on application of ice gel packTimepoint: In the 2 min duration that the ice gel pack is applied on the patients hand;To compare the dose of propofol needed for induction between the lignocaine pretreatment group and ice gel pack therapy groupTimepoint: Not applicable;To compare the hemodynamic changes including blood pressure and heart rate, at the time of induction, between the two groupsTimepoint: Before and after induction of Anaesthesia

Countries

India

Contacts

Public ContactDr Yojana Karki

Postgraduate Institute of Medical Education and Research (PGIMER)

dr.rajeevchauhan@gmail.com7087422950

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 11, 2026