Scope of a specified blood component instillation into the womb for improving pregnancy rate

Scope of PRP for endometrial receptivity-randomized controlled trial - SCOPE TRIAL

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/04/032927

Enrollment

186

Registered

2021-04-19

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N972- Female infertility of uterine origin

Interventions

Intervention1: Platelet Rich Plasma: Intrauterine instillation of autologous concentrated platelet rich plasma in women undergoing embryo transfer

Eligibility

Inclusion criteria

Inclusion criteria: All women aged <40 years with a history of recurrent implantation failure undergoing frozen embryo transfer.

Exclusion criteria

Exclusion criteria: BMI > 30 kg/m2, Congenital and untreated acquired uterine cavity abnormalities, Untreated hydrosalpinx, Poor ovarian responders as per Bologna criteria, , Women undergoing PGT cycle, women with thin endometrium <8 mm in the index frozen embryo transfer cycle, Thrombophilia positive, Uncontrolled endocrine and hematologic dysfunction, Severe male factor infertility, Difficult embryo transfer, Poor quality embryos .

Design outcomes

Primary

Measure	Time frame
Ongoing Pregnancy Or Live Birth RateTimepoint: after 20 weeks	—

Secondary

Measure	Time frame
b-hCG positive rate Clinical Pregnancy Rate Miscarriage RateTimepoint: After 6 weeks -20 weeks	—

Countries

India

Contacts

Public ContactDr Noushin Abdul Majiyd

Craft Hospital and research Centre

drnoshinashraf@gmail.com9544240002

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026