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To Analyse Changes in the Levels of Salivary Lysozyme in Partially Edentulous Patients Before and After Removable Prosthetic Treatment among

Comparative Analysis of Changes in the Levels of Salivary Lysozyme Before and After Removable Prosthetic Treatment among Partially Edentulous Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/04/032899
Enrollment
40
Registered
2021-04-16
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z00-Z99- Factors influencing health status and contact with health services Health Condition 2: K084- Partial loss of teeth

Interventions

Intervention1: Fabriaction of Removable Partial Denture: The changes in the levels of salivary lysozyme before i.e. at 0 months and after 3 months of RPD insertion Control Intervention1: Not Applicabl

Sponsors

DrShefali Dogra
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients having partially edentulous arches with more than 3 and less than 6. Age group between 35-60 years. Patients who are non-smokers. Patients wearing dentures for the first time.

Exclusion criteria

Exclusion criteria: Patients with very poor oral hygiene having OHI-S score between 3.1-6.0. Patients taking any kind of medications which may affect salivary secretions from last 3 months. Pregnant and lactating females.

Design outcomes

Primary

MeasureTime frame
To find correlation between concentrations of Lysozyme before i.e. baseline and after three months after insertion of removable partial denture in successive samples of unstimulated saliva collected from partially edentulous patients. Timepoint: The study is conducted at baseline i.e. at 0 months and after 3 months of denture insertion.

Secondary

MeasureTime frame
To compare the changes in the level of salivary lysozyme before and after the RPD insertionTimepoint: 3 months

Countries

India

Contacts

Public ContactDrShefali Dogra

MRIIRS

dhawan.mrdc@mrei.ac.in9810050103

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026