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correlation of standard radiation dose delivered with symptoms of the patient

â??Correlation of Radiation dose to the peri-tumoral Edema volume and Symptoms with Quality of life in High-grade Gliomas - CRESH

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/04/032897
Enrollment
40
Registered
2021-04-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C719- Malignant neoplasm of brain, unspecified

Interventions

Intervention1: nil: nil

Sponsors

MPMMCC
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Histopathological tissue diagnosis of high-grade glioma 2. KPS >=70 3. Age >18 and 4. Fit to receive radiotherapy 5. Has undergone definitive Surgery 6. Willing to fill informed consent form

Exclusion criteria

Exclusion criteria: 1. Any prior history of radiation to brain 2. Age less than 18yrs or more than 70 yrs 3. Any KPS 4. Low grade gliomas

Design outcomes

Primary

MeasureTime frame
1. Tumor response (RANO criteria) 2. Change in edema volume at pre-RT, 3, 6, 12, 18- and 24-months post radiotherapy 3. Grade of symptoms and QOL scores at pre-RT, 3, 6, 12, 18- and 24-months post radiotherapy. 4. Disease free Survival, 1-year survival and 2-year survival. 5. 3 yr OS Timepoint: 1. Tumor response (RANO criteria) 2. Change in edema volume at pre-RT, 3, 6, 12, 18- and 24-months post radiotherapy 3. Grade of symptoms and QOL scores at pre-RT, 3, 6, 12, 18- and 24-months post radiotherapy. 4. Disease free Survival, 1-year survival and 2-year survival. 5. 3 yr OS—

Secondary

MeasureTime frame
nillTimepoint: nill—

Countries

India

Contacts

Public ContactDR AJAY GV

MPMMCC(Mahamana Pandit Madan Mohan Malviya Cancer Centre)

drajaygv85@gmail.com9844507828

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026