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Decreasing in the incidence of pain component while injection during unconsciouness of the person

Comparison of effect of low dose ketamine and lignocaine pretreatment in prevention of pain on propofol injection (POPI) during general anaesthesia for elective surgeries - -

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/04/032881
Enrollment
50
Registered
2021-04-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: Low dose Ketamine and Lignocaine: Dose :Group K patients receive 100mcg/kg of ketamine intravenously and Group L patients receive 0.5 mg/kg of 2% lignocaine intravenously withou

Sponsors

Dr Aravind
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA 1 and 2 patients 2.Age more than 18 years 3.Patients undergoing general anaesthesia 4.Patients acceptance 5.Patients with Propofol as induction agent

Exclusion criteria

Exclusion criteria: 1.Patients allergic to Propofol and Ketamine 2.Patients allergic to egg 3.Patietns with cardiovascular, neurologica and respiratory diseases 4.ASA 3 and 4 5.Emergency Surgeries

Design outcomes

Primary

MeasureTime frame
The primary outcome of this study is to compare the effect of low dose ketamine and 2% lignocaine pretreatment in preventing pain on propofol injection (POPI ) with verbal rating scale ( 0-3 ) and its haemodynamic responses. Timepoint: The primary outcome of this study is to compare the effect of low dose ketamine and 2% lignocaine pretreatment in preventing pain on propofol injection (POPI ) with verbal rating scale ( 0-3 ) and its haemodynamic responses. Assessed during injection, o minute, 1,2,3 and 5 minutes and the outcome is predicted.

Secondary

MeasureTime frame
Haemodynamic parameters like heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure and oxygen saturation monitoredTimepoint: every one minute till 10 minutes

Countries

India

Contacts

Public ContactR Arun Kumar

PSG IMSR, Coimbatore, India

shivaaniarun76@gmail.com09944113440

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026