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The effect of drug dexmedetomidine nebulization on circulatory parameters due to laryngoscopy and intubation in patients during general anaesthesia

The effect of preoperative dexmedetomidine nebulization on the haemodynamic response to laryngoscopy and intubation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/04/032855
Enrollment
104
Registered
2021-04-15
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: T885- Other complications of anesthesia

Interventions

Intervention1: Dexmedetomidine drug: Dexmedetomidine 50 mcg (mixed with saline to a total volume of 5 ml) nebulization will be administered to Group D(study group) and 5 ml saline nebulization to Grou

Sponsors

Government Medical College and Hospital Chandigarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. American Society of Anaesthesiologist(ASA) physical status I and II. 2. Age group between 18 to 60 years.

Exclusion criteria

Exclusion criteria: 1. Patients with anticipated difficult airway (Airway Difficulty Score >8). 2. Patients with a body mass index (BMI) >35kg/m2 3. Patients with uncontrolled hypertension. 4. Patients with known allergy to study drug. 6. Pregnant patients.

Design outcomes

Primary

MeasureTime frame
The primary aim will be to evaluate the effects on the heart rate and blood pressure response in adult patients.Timepoint: The time points will be the baseline parameters, before nebulization, after nebulization, 1 min after intubation, 5 min after intubation, 10 min after intubation and 2 hrs postop

Secondary

MeasureTime frame
The secondary aims will be to evaluate the postoperative pain and sore throat.Timepoint: The secondary aims will be evaluated 2 hours postoperatively.

Countries

India

Contacts

Public ContactDr Lakesh K Anand

Government Medical College and Hospital , Chandigarh

lkanand11@gmail.com9646121522

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026