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Antimicrobial effect of two different medicaments introduced inside the root canal for reducing the bacterial load

A Comparative Evaluation of the Efficiency of Octenidine Dihydrochloride and Calcium Hydroxide as an Intracanal Medicament: A Randomized Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/04/032838
Enrollment
48
Registered
2021-04-15
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K045- Chronic apical periodontitis

Interventions

Intervention1: Octenidine Dihydrochloride: After complete cleaning and shaping of the canal using Protaper gold rotary system and sodiym hypochlorite, EDTA and saline, 0.05% Octenidine would be insert

Sponsors

Dr Rukhsaar Gulzar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Teeth indicated for root canal treatment with apical periodontitis. Healthy person between the age group of 18-50, giving a signed consent

Exclusion criteria

Exclusion criteria: Retreatment cases Completely calcified canals Internal Resorption

Design outcomes

Primary

MeasureTime frame
Reduction in bacterial load determined by colony forming unit (CFU)Timepoint: CFU analysis at base level (S1) after access opening. CFU analysis after complete cleaning and shaping (S2). CFU analysis after one week of medicament placement in the canal (S3)—

Secondary

MeasureTime frame
Reduction in painTimepoint: preoperative pain, pain after 24 hours and after one week of follow up determined by VAS pain scale—

Countries

India

Contacts

Public ContactDr Iffat Nasim

Saveetha Dental College

nasimiffat@gmail.com9940063567

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026