Evaluation of effect of Shallaki, Lepa and Janu Vasti in Patients With Knee Joint Osteoarthritis

Clinical Evaluation of Shallaki and its comparative synergistic effect with Lepa and Janu Vasti in Janusandhigata Vata with special reference to Knee Joint Osteoarthritis

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/04/032807

Enrollment

Registered

2021-04-13

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M170- Bilateral primary osteoarthritis of knee

Interventions

Intervention1: Shallaki Tablets : Shallaki tablets 1 gram TDS orally 15 days, Control Intervention1: Shallaki Tablets with Koladi Lepa: Internal Application of Shallaki tablet 1 gram TDS for 15 days

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients in the age group of 40 to 70 years of either sex. 2. Patients having signs and symptoms of Janusandhigata Vata of Shotha (edema), Vatapurnadriti Sparsha (on palpation revealed as air filled bag) and pain with Prasaran (extension) and Akunchan (flexion) movements. 3. Patients having chronicity of disease Janusandhigata Vata (KOA) for less than 5 years. 4. Patients willing to sign consent form for the clinical trial. 5. Kellgren Lawrence (Radiological scale) of eâ?? >=2

Exclusion criteria

Exclusion criteria: 1. Patients below 40 years and above 70 years of age. 2. Patients of Rheumatoid arthritis, Ankylosing and traumatic arthritis. 3. Patients suffering from paralysis, muscular dystrophy, polio affected persons or persons with bony deformities 4. Patients having systemic conditions such as Tuberculosis, Brucellosis, Osteomyelitis, Gouty Arthritis, Psoriatic Arthritis and Systemic Lupus Erythematosus 5. Patients having neoplasm of spine and other complicated diseases like CCF, DM, Uncontrolled HTN, Unstable Angina, Recent MI etc. 6. Patients using anti-inflammatory medicines including Allopathic medicine and AYUSH medicines.

Design outcomes

Primary

Measure	Time frame
Reduction in pain and stiffness including signs and symptoms of Janusandhigata Vata of Shotha (edema), Vatapurnadriti Sparsha (on palpation revealed as air filled bag) and pain with Prasaran (extension), Akunchan (flexion) movements and improvement in Knee Injury and Osteoarthritis Outcome Score (KOOS)Timepoint: 15 days	—

Secondary

Measure	Time frame
Improvement of range of motionTimepoint: 15 days	—

Countries

India

Contacts

Public ContactAbhishek Upadhyay

National Institute of Ayurveda

dr.abhishek82@gmail.com9915613039

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026