COMPARISON OF ORAL MELATONIN AND CLONIDINE AS PREMEDICATION ON PERIOPERATIVE ANALGESIC REQUIREMENT IN LAPAROSCOPIC CHOLECYSTECTOMY.

COMPARATIVE EVALUATION OF ORAL MELATONIN AND ORAL CLONIDINE AS PREMEDICATION ON PERIOPERATIVE ANALGESIC REQUIREMENT IN PATIENTS UNDERGOING LAPAROSCOPIC CHOLECYSTECTOMY: PROSPECTIVE RANDOMISED DOUBLE BLIND STUDY

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/04/032786

Enrollment

Registered

2021-04-13

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: DRUG MELATONIN 6MG: PREOPERATIVELY, ORAL MELATONIN 6MG WILL BE GIVEN TO RANDOMLY SELECTED ASA I OR II PATIENTS 60 MINS PRIOR TO INDUCTION IN ELECTIVE LAPAROSCOPIC CHOLECYSTECTOMY. Contr

Eligibility

Inclusion criteria

Inclusion criteria: ASA I OR II PATIENTS, POSTED FOR ELECTIVE LAPAROSCOPIC CHOLECYSTECTOMY

Exclusion criteria

Exclusion criteria: 1. ASA III, ASA IV PATIENTS 2. EMERGENCY PATIENTS 3. MORBID OBESITY (BMI >35) 4. AGE >65 OR 5. ANTICIPATED DIFFICULT AIRWAY (INTUBATION DURATION >15 SEC) 6. ALLERGIC TO STUDY DRUG 7. PREGNANCY 8. DURATION OF SURGERY >120 MIN 9. H/O DRUG ABUSE 10. PATIENT ON STEROIDS, ANTIPSYCHOTICS, ANTICHOLINERGICS 11. UNABLE TO COMPREHEND 12. REFUSAL FOR CONSENT

Design outcomes

Primary

Measure	Time frame
TO COMPARE EFFICACY OF ORAL MELATONIN VERSUS ORAL CLONIDINE IN PERIOPERATIVE ANALGESIATimepoint: 1. BASELINE 2.0 MINUTE, 30 MINUTES, 1 HOUR, 2 HOUR, 6 HOURS POSTOPERATIVELY	—

Secondary

Measure	Time frame
TO COMPARE EFFICACY OF ORAL MELATONIN AND ORAL CLONIDINE ON- 1. ANXIETY SCORE 2. POSTOP DELIRIUM 3. COGNITION 4. SEDATIONTimepoint: BASELINE PRIOR TO PREMEDICATION. AFTER PREMEDICATION. POSTOP (0 MIN, 30 MIN, 1 HOUR, 2HOUR, 6 HOUR)	—

Countries

India

Contacts

Public ContactVIKRAM MADAAN

FORTIS HOSPITAL, MOHALI

drkat22in@gmail.com9872217274

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026