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Cognitive Behavioral Therapy vs Yoga nidra in Psychogenic Non-epileptic seizures

A Randomised Controlled Trial Comparing the Efficacy of Cognitive Behavioral Therapy vs Yoga Nodra in Persons with Psychogenic Non-epileptic Seizures

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/04/032758
Enrollment
50
Registered
2021-04-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F448- Other dissociative and conversiondisorders

Interventions

Intervention1: Cognitive Behavioral Therapy vs Yoga Nidra in PNES patients: Arm A- CBT+ Yoga idra Arm B-CBT+Sham Yoga nidra Intervention2: Cognitive Behavioral Therapy and Yoga nidra: Given after rand

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: i)Persons aged 18-70 years ii) Clinical diagnosis of PNES confirmed by home video and a similar episode induced in video-EEG with no ictal correlates

Exclusion criteria

Exclusion criteria: : i) A coexistent diagnosis of epilepsy (past/current) ii) Current drug/alcohol dependence iii) Patients with episode frequency iv) Patients with coexisting non-neurologic comorbidities like chronic cardiac, renal and other systemic diseases v)Patients not giving consent vi) Patients with intellectual disability vii) Patients with acute psychosis

Design outcomes

Primary

MeasureTime frame
Reduction in monthly episode frequency, measured at baseline and the end of study- i.e. 6 months Timepoint: 0, 6 months

Secondary

MeasureTime frame
i) Duration of freedom from episodes ii) Change in quality of life, measured by QOLIE-31 iii) Reduction in use of anti-seizure drugs iv) Improvement in psychological comorbidities, measured by HAMA and HAMD scales at baseline and end of 6 months v) Cost difference between CBT and YN Timepoint: 0,6 months

Countries

India

Contacts

Public ContactProf Manjari Tripathi

All India Institute of Medical Sciences, New Delhi

mantriaiims@gmail.com01126594494

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026