Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: MIDAZOLAM: This group will receive single dose of 0.04 mg/kg IV of Inj. Midazolam after induction .30 minutes prior to extubation,single dose of Inj. Ondansetron 0.1mg/kg IV will be gi
Sponsors
Bangalore Baptist hospital
Eligibility
Inclusion criteria
Inclusion criteria: Laparoscopic surgeries Middle ear surgeries Gynaecological surgeries Breast surgeries Cholecystecomies BMI
Exclusion criteria
Exclusion criteria: Smokers Pregnant/lactating women Use of nitrous oxide intraoperatively Patients having history of motion sickness/ PONV Patients on chronic steroid therapy Patients on chronic opiod analgesics Patients on preoperative chemotherapy Patients who receive antiemetic/steroid 24 hrs prior to commencement of study Patients suffering from diabetes mellitus with autonomic neuropathy, intestinal obstruction, hiatus hernia, hepatic and renal diseases Patients with neurological diseases/ Neuromuscular diseases Patients with prolonged QTC interval Patients on CNS depressant drugs Patients with psychiatric illness or cognitive impairment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the effectiveness of Midazolam and Ondansetron Vs Dexamethasone and Ondansetron in prophylaxis of Post operative Nausea Vomiting in female patients undergoing emetogenic surgeries.Timepoint: 24 hrs | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Total dose of rescue antiemetic required 2.Total episodes of Nausea and Vomiting 3.Sedation score postoperativelyTimepoint: 1hr , 6hr , 12 hr | — |
Countries
India
Contacts
Public ContactDr Yashaswini H Raya
Bangalore Baptist Hospital
Outcome results
None listed