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Immunity after vaccination in people who have suffered from COVID-infection and people who have never been infected with corona

SARS-CoV-2: Comparison of active immunity acquired by natural exposure versus inoculation of HCW

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/04/032729
Enrollment
64
Registered
2021-04-12
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere

Interventions

None listed

Sponsors

Rajiv Gandhi Cancer Institute and Research Centre
Lead Sponsor
Dr Rajiv Chawla
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Health Care Worker Employed at Rajiv Gandhi Cancer Institute History of positive RT-PCR test for SARS-CoV-2 Either moderate (4.62-18 AU) or high ( >18 AU) IgG antibody titre Vaccinated against COVID-19

Exclusion criteria

Exclusion criteria: Non-Health Care Worker Not employed at Rajiv Gandhi Cancer Institute Not vaccinated against COVID-19

Design outcomes

Primary

MeasureTime frame
IgG antibody titreTimepoint: 7-14 days post first dose of vaccination 28 days post second dose of vaccination—

Secondary

MeasureTime frame
FeverTimepoint: 0-3 days post first dose of vaccination 0-3 days post second dose of vaccination;ChillsTimepoint: 0-3 days post first dose of vaccination 0-3 days post second dose of vaccination;MyalgiaTimepoint: 0-3 days post first dose of vaccination 0-3 days post second dose of vaccination;HeadacheTimepoint: 0-3 days post first dose of vaccination 0-3 days post second dose of vaccination;RashTimepoint: 0-3 days post first dose of vaccination 0-3 days post second dose of vaccination;Pain at injection siteTimepoint: 0-3 days post first dose of vaccination 0-3 days post second dose of vaccination;MalaiseTimepoint: 0-3 days post first dose of vaccination 0-3 days post second dose of vaccination;Any other symptomTimepoint: 0-3 days post first dose of vaccination 0-3 days post second dose of vaccination;MedicationTimepoint: 0-3 days post first dose of vaccination 0-3 days post second dose of vaccination—

Countries

India

Contacts

Public ContactDr Shagun Bhatia Shah

Rajiv Gandhi Cancer Institute and Research Centre

drshagun_2010@rediffmail.com9891769779

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026