Health Condition 1: K703- Alcoholic cirrhosis of liver Health Condition 2: K74- Fibrosis and cirrhosis of liver Health Condition 3: K746- Other and unspecified cirrhosis ofliver Health Condition 4: K743- Primary biliary cirrhosis Health Condition 5: K744- Secondary biliary cirrhosis
Conditions
Interventions
Control Intervention1: Nil: Nil
Sponsors
Dr Philip Abraham
Eligibility
Inclusion criteria
Inclusion criteria: 1.Consenting patients with cirrhosis of liver attending the outpatient / inpatient services of Division of Gastroenterology. Cirrhosis of liver is defined as the histological development of regenerative nodules surrounded by fibrous bands in response to chronic liver injury, that leads to portal hypertension and end stage liver disease In clinical practice, the diagnosis is based on a combination of clinical, biochemical and radiological findings with or without evidence of varices on endoscopic evidence. 2. Age above 18 years
Exclusion criteria
Exclusion criteria: Patients with tuberculosis, cancer or other severe co-morbidities that will affect the outcome independently will be excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To determine the incidence of renal dysfunction in liver cirrhosis patients 2. To classify patients into various categories such as AKI (prerenal, HRS-AKI, ATN, and postrenal) as per the ICA-AKI criteria, AKI-on-CKD, and CKD as per the KDIGO definition 3. To calculate FENa in patients with AKI 4. To classify patients with HRS into HRS AKI and HRS NAKI as per new definitions Timepoint: After 6 months of recruitment | — |
Secondary
| Measure | Time frame |
|---|---|
| To study the clinical outcome of patients with liver cirrhosis with renal dysfunction over a follow-up of 6 monthsTimepoint: After 6 months of recruitment | — |
Countries
India
Contacts
Public ContactDr Vinita Patil
P. D. Hinduja Hospital and Medical Research Centre
Outcome results
None listed