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To known the effect of two different dose of iv dexamethasone on patients undergoing surgery under spinal anaesthesia.

To evaluate the efficacy of two different doses of intravenous dexamethasone on the duration of subarachnoid block in patients undergoing infraumbilical surgery : A randomized control double blind study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/04/032685
Enrollment
90
Registered
2021-04-08
Start date
Unknown
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: -

Interventions

Intervention1: Dexamthasone: Intravenous Dexamethasone 4mg or 8mg,according to the patient group will be given during the subarachnoid block. Control Intervention1: Normal Saline: 2ml of normal saline

Sponsors

DR MAYA DEHRAN
Lead Sponsor
Department of anaesthesiologyPain Medicine and Critical care
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 and 2, infra umbilical surgery,duration of surgery less than or equal to 3hrs, BMI less than or equal to 30

Exclusion criteria

Exclusion criteria: Patient refusal,long term steroid therapy,allergy to dexamethasone,patient with diabetes mellitus,alcoholic abuse,addiction t opioids and chronic use of other analgesic drug,neurological and psychological disorders, chronic back ache,sepsis,infection at local site.

Design outcomes

Primary

MeasureTime frame
Duration of sensory and motor blockade during subarachnoid blockTimepoint: Sensory blockade will be till 4 dermatomes regression.motor block from bromage score 0 to 3.

Secondary

MeasureTime frame
1) Time of onset of sensory block and motor blockage. 2) Duration of post op analgesia and total dose of analgesic needed in first 24hr. 3) Effect on blood sugar levels. 4) Haemodynamics and other side effects – Post operative nausea and vomiting (PONV), itching and respiratory depression. 5) Ramsay sedation score for level of sedation. Timepoint: 1)Onset time of sensory block will be defined as the time from injection of drugs into the intrathecal space to peak of sensory blockade.Onset of motor block will be defined as the time from intrathecal injection of drug until the modified Bromage scale is 3. 2) The time to the first bolus dose will be recorded as the first analgesic requirement during first 24 hours.

Countries

India

Contacts

Public ContactSumanth S

All India institute of medical sciences New delhi

Mayadehran@yahoo.com8800497195

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026