Comparison of two drugs dexmedetomidine and ketamine in children given through nose.

Comparison of intranasal dexmedetomidine and ketamine for paediatric premedication: A randomized study.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/04/032662

Enrollment

100

Registered

2021-04-08

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Intranasal ketamine: 5 mg/ Kg body weight, single dose, intranasal route, day of surgery Control Intervention1: Intranasal Dexmedetomidine: 1 microgm/ Kg body weight, single dose, intra

Eligibility

Inclusion criteria

Inclusion criteria: patients able to comprehend and willing to participate. Patients of ASA physical status 1 and 2.

Exclusion criteria

Exclusion criteria: patients with known sensitivity to given drugs. patients on concomitant anti arrhythmic or sedative medication. patients with history of nausea/vomiting, apnoeic spells,cardiorespiratory and neurological illnesses.

Design outcomes

Primary

Measure	Time frame
FLACC scoringTimepoint: 45 minutes	—

Secondary

Measure	Time frame
Preoperative anxiety score, acceptance of intranasal delivery, sedation score and any adverse effect.Timepoint: 60 minutes	—

Countries

India

Contacts

Public ContactPrakash K Dubey

Indira Gandhi Institute of Medical Sciences

doctornehakumari1@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026