Health Condition 1: L811- Chloasma
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
IADVL Academy
Eligibility
Inclusion criteria
Inclusion criteria: Case- Adult women in the reproductive age group suffering from Melasma attending the dermatology outpatient department. Control- Age-matched otherwise healthy women of reproductive age group without Melasma attending the dermatology outpatient department.
Exclusion criteria
Exclusion criteria: 1. Pregnant, lactating and post-menopausal women 2. Women with the irregular menstrual cycle, polycystic ovary disease and a history of endocrinopathies. 3. Women on oral contraceptive pills, intrauterine device and hormone replacement therapy 4. Facial dermatitis 5. Albinos 6. History of intake of drugs known to exacerbate Melasma 7. Patients with allergic diseases or bone diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| After completing the patients based on this study and its further validation will be done on cell lines and animal model-based study. Further, MITF expression and Hormonal status if able to provide any significant correlation then more precise therapeutic interventions could be planned, so it may help in providing better management to women suffering from Melasma.Timepoint: 2 years. | — |
Secondary
| Measure | Time frame |
|---|---|
| The current study on reproductive hormones with MITF may open new vistas in the understanding of the Melasma disease along-with corresponding drug targets so that better management could be achieved.Timepoint: 2 years. | — |
Countries
India
Contacts
Public ContactDr Sunil Kumar Gupta
All India Institute of Medical Sciences, Gorakhpur
Outcome results
None listed