Health Condition 1: O746- Other complications of spinal andepidural anesthesia during labor and delivery
Conditions
Interventions
Intervention1: Administration of two different doses of ondansetron, fixed dose(group F) and weight adjusted dose (group W) 5 min before administration of spinal anaesthesia: Group F -Patients will re
Sponsors
Vardhman Mahavir medical college and Safdarjung hospital New delhi
Eligibility
Inclusion criteria
Inclusion criteria: Parturients aged 20 to 40 years, of American society of anaesthesiologists physical status 1 and 2, with term singleton pregnancy scheduled for elective caesarean delivery under spinal anaesthesia.
Exclusion criteria
Exclusion criteria: 1. Parturients with diabetes, hypertension, other cardiovascular, respiratory or hepatorenal disease, obesity (BMI >30kg/m) complicated pregnancy, foetal abnormality or distress. 2. Coagulopathy, thrombocytopenia, or any contraindications to spinal anaesthesia 3. Allergy to study medication or patients receiving 5 hydroxytryptamine reuptake inhibitors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the Incidence of post spinal hypotension in parturients receiving preoperative, fixed dose with weight adjusted dose of intravenous ondansetronTimepoint: From time of administration of spinal anaesthesia till the end of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of maternal bradycardia Incidence of nausea and vomiting. Neonatal outcome as assessed by APGAR ScoreTimepoint: Heart rate and Blood pressure will be noted every 2 minute till delivery of baby and then every 5 min till end of surgery. Neonatal APGAR score at 1 min and 5 min will be determined by attending paediatrician | — |
Countries
India
Contacts
Public ContactDr Alwin Thomas
Vardhman Mahavir medical college and Safdarjung Hospital. New Delhi
Outcome results
None listed