Health Condition 1: N179- Acute kidney failure, unspecified
Conditions
Interventions
Intervention1: FRUSEMIDE STRESS TEST: Frusemide stress test
Injection Frusemide 0.04mg per kg per hour is administered intravenously for 2 hours. A
positive response is taken as a urine output 1.5ml/k
Sponsors
Mehta Multispeciality Hospitals Pvt Ltd
Eligibility
Inclusion criteria
Inclusion criteria: a. Urine Output less than 1ml/Kg/ hour for minimum 6hours (KDIGO 1) b. Incremental Fluid Overload ( >1%) in two consecutive 6 hourly quadrants of Fluid Overload assessment. c. Clinical evidence of pulmonary fluid overload with no identified pre-existing heart disease
Exclusion criteria
Exclusion criteria: a. Children who are in AKI KDIGO stages III at the time of hospitalization. b. Children who are known cases of CKD
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess Maximum KDIGO stage at 24 hours of completion of frusemide trial in responders Vs non responders - Assessed by creatinine at 24 and 48 hours of completing frusemide trial. . To compare discharge creatinine and eGFR by CKiD Creatinine formula among responders Vs non responders.Timepoint: Followed up at 24hours and 48 hours of completion of frusemide trial | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety of Frusemide assessed by hearing evaluationTimepoint: 3 months after discharge from hospital | — |
Countries
India
Contacts
Public ContactArathy Krishnan
Mehta Multispeciality Hospitals Pvt Ltd
Outcome results
None listed